Tag Archives: cardiac simulation

Publication and Validation of Ionic Models

The authors of ionic models (see also the list of ionic models we currently offer) are typically wet-lab savvy — they patch-clamp cells and run special experiments on them, stepping voltage up and down and whatnot, to understand the behavior … Continue reading

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CardioSolv’s CARP Simulator in the News

“Medical science is increasingly turning to computational models to study the possible effects of drugs and surgical interventions, before moving on to patient trials. One active area of research is in heart modelling. The structure of a patient’s heart can … Continue reading

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Save an animal – run a simulation

Perhaps you’ve heard about the passionate protests opposing animal research (and the counter-protests supporting it). Whether you’re opposed to animal research altogether, want to minimize it to avoid it as much as possible, or just want to avoid the cost … Continue reading

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Cardiac Simulation – Cellular (ionic) Models

This is the second post in a series of posts about the hows and whys of cardiac simulation, both electrophysiological and mechanical. The first and previous post was Conceptual Background. In this post, I’ll catalog the ionic models and plug-ins … Continue reading

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Monodomain vs Bidomain

When modeling cardiac tissue, there are two dominant approaches: bidomain, in which both the intra- and extracellular spaces of the tissue are represented, and monodomain, in which only the intracellular space is represented. The bidomain approach is essential when the … Continue reading

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